Discovery of non-invasive biomarkers for the diagnosis of endometriosis

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Evaluation of endometrial biomarkers for semi-invasive diagnosis of endometriosis.

OBJECTIVE To test the hypothesis that specific proteins and peptides are expressed differentially in eutopic endometrium of women with and without endometriosis and at specific stages of the disease (minimal, mild, moderate, or severe) during the secretory phase. DESIGN Patients with endometriosis were compared with controls. SETTING University hospital. PATIENT(S) A total of 29 patients ...

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15 صفحه اول

Non-invasive diagnosis of endometriosis based on a combined analysis of six plasma biomarkers.

BACKGROUND Lack of a non-invasive diagnostic test contributes to the long delay between onset of symptoms and diagnosis of endometriosis. The aim of this study was to evaluate the combined performance of six potential plasma biomarkers in the diagnosis of endometriosis. METHODS This case-control study was conducted in 294 infertile women, consisting of 93 women with a normal pelvis and 201 wo...

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ژورنال

عنوان ژورنال: Clinical Proteomics

سال: 2019

ISSN: 1542-6416,1559-0275

DOI: 10.1186/s12014-019-9235-3